Label-Free Detection of Biopolymer Using Terahertz Waves
نویسندگان
چکیده
منابع مشابه
Label-free bioaffinity detection using terahertz technology.
We report the first use of differential terahertz time-domain spectroscopy for bioaffinity sensing. Binding is observed by measuring the transmission of a thin layer of biotin bound to the sensor protein avidin. We demonstrate the THz wave transmission of a sub-micron-thick film and sensitivity to 0.1 microg cm(-2) of biotin. These results point the way for a host of biosensor applications usin...
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A new affinity biosensor based on pulsed terahertz (THz) wave technology has been used to monitor binding between biotin and avidin molecules. Amplified detection of avidin-biotin binding is obtained on supported membranes composed of biotin layers on quartz surface, which is modified with octadecanol. Agarose particles are conjugated with avidin and then applied to biotin, which is already bou...
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ژورنال
عنوان ژورنال: Journal of the Spectroscopical Society of Japan
سال: 2008
ISSN: 1884-6785,0038-7002
DOI: 10.5111/bunkou.57.228